Reducing phylogenetic bias in correlated mutation analysis
نویسندگان
چکیده
منابع مشابه
Reducing phylogenetic bias in correlated mutation analysis.
Correlated mutation analysis (CMA) is a sequence-based approach for ab initio protein contact map prediction. The basis of this approach is the observed correlation between mutations in interacting amino acid residues. These correlations are often estimated by either calculating the Pearson's correlation coefficient (PCC) or the mutual information (MI) between columns in a multiple sequence ali...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 2010
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/gzp078